Epigenetic health
Epigenetic Markers Predict Type 2 Diabetes Patients Who Respond to, Tolerate Metformin | GenomeWeb
NEW YORK – Epigenetic markers can distinguish between individuals with type 2 diabetes who respond to metformin treatment and those who do not, a new study has found. Metformin is commonly prescribed to individuals with type 2 diabetes, but about 30 percent of...
Fasting, Longevity and the Mitochondrial Connection | by Dr. Jason Fung | Personal Growth | Medium
The most well recognized role of mitochondrion is as the cell’s powerhouse, or energy producer. It generates energy in the form of ATP using oxidative phosphorylation (OxPhos). Organs (heart is #1, and kidney is #2 in terms of ATP usage) that use a lot of oxygen, or...
Gene-diet interaction and precision nutrition in obesity
The rapid rise of obesity during the past decades has coincided with a profound shift of our living environment, including unhealthy dietary patterns, a sedentary lifestyle, and physical inactivity. Genetic predisposition to obesity may have interacted with such an...
Epigenetics and Metabolism in Health and Disease
In the next 10 years, one billion people are estimated to suffer from disabling consequences of metabolic disorders, making them the number one noncommunicable disease on a global scale by 2030. Lots of risk factors such as dietary intake, lack of exercise and other...
BLUEZONES® ELEMENTS › The Concept › My personal bluezone
WHO YOU ARE IS YOUR DECISION Your daily routine and behaviours can have a major impact on your highly complex genetic system which is composed of aspects such as eating habits, environmental stimulation, stress management, social interaction and overall lifestyle....
Low-Cal Diet Could Change Epigenetic Patterns in Obesity-Related Disease | What is Epigenetics?
Obesity is a disease characterized by excessive body fat. It can be caused by environment, a person’s early-life nutrition, and it can even be a result of their parent’s diet. Obesity is so dangerous because associated with many diseases such as hypertension, type-2...
Exercise Prevents Diet-Induced Cellular Senescence in Adipose Tissue
Considerable evidence implicates cellular senescence in the biology of aging and chronic disease. Diet and exercise are determinants of healthy aging; however, the extent to which they affect the behavior and accretion of senescent cells within distinct tissues is not...
Senolytic Treatment with Dasatinib and Quercetin Confirmed to Reduce the Burden of Senescent Cells in Human Patients – Fight Aging!
While senescent cells are important in a range of beneficial processes, from cancer suppression, to the Hayflick limit, to wound healing, their presence is temporary in all such cases. Near all are destroyed, either by programmed cell death or by the immune system....
Intermittent Fasting and Autophagy: All that you need to know about this age-old practise
Intermittent fasting and ketogenic diets are known to trigger a process known as autophagy. The Greek origin word literally means ‘self’ and ‘eating,’ and that is exactly what happens to your body during the process – it eats damaged cells to regenerate newer cells....
Dawn-to-sunset fasting suggests potential new treatment for obesity-related conditions: Study of 30-day Ramadan fast shows promising implications for timing and duration between meals — ScienceDaily
Fasting from dawn to sunset for 30 days increased levels of proteins that play a crucial role in improving insulin resistance and protecting against the risks from a high-fat, high-sugar diet, according to research presented at Digestive Disease Week® (DDW) 2019. The...
