Polyphenols, saffron, and probiotics have shown promising effects in alleviating symptoms of depression through various biological mechanisms:Polyphenols exert antioxidant and anti-inflammatory effects, which can reduce neuroinflammation and oxidative stress—both implicated in depression. They may also enhance neurogenesis and modulate neurotransmitter pathways, such as serotonin and dopamine.Saffron, a spice derived from Crocus sativus, has been found in several clinical studies to be effective Its active compounds (like crocin and safranal) appear to boost serotonin levels and have neuroprotective and mood-stabilizing properties.Probiotics, beneficial gut bacteria, can influence the gut-brain axis, reducing depressive symptoms by improving gut microbiota balance, lowering systemic inflammation, and producing neuroactive compounds (like GABA and serotonin precursors).
Polyphenols saffron probiotics depression
